Scientific Fraud Growing Exponentially
/Nowhere is the attack on science more evident than in the burgeoning incidence of scientific fraud, in the form of both falsification and fabrication of observational data. I first wrote about this in a blog post in 2019, since when the problem has only escalated. It’s now estimated that 1% to 2% of all scientific research papers are fraudulent – a fraud rate approaching that of industries such as healthcare and financial services.
A recent study from Northwestern University has examined scientific fraud in depth. Rather than the traditional focus on scientific misconduct by lone individuals, which is comparatively rare, the new study exposes numerous instances of large-scale fraud enabled by a far-flung network of editors and authors who cooperate to publish low-quality or fabricated research papers. This coordinated fraud combines clandestine “paper mills,” intermediary brokers, and so-called predatory journals that charge a fee without offering any services other than publication itself.
Paper mills are shady businesses that sell bogus manuscripts and authorships to researchers who need journal publications to advance their careers. The Northwestern researchers say that a 2022–23 survey of medical residents at hospitals in southwest China found that 47% of respondents had bought and sold papers, allowed other people to write their papers, or written papers for others.
A 2023 report in Nature magazine identified more than 400,000 research articles published over the previous two decades that show strong textual similarities to known studies produced by paper mills; the rising trend is illustrated in the figure below.
The new Northwestern study assembled an extensive database derived from major aggregators of the scientific literature, retracted publications, editorial records, and reports of image duplication in research papers.
A portion of the study focused on the massive online open access journal PLOS ONE, which has a higher-than-average retraction rate. The journal also lists the handling editor of every published paper. Of PLOS ONE editors who have accepted articles for publication, 22 accepted papers that were later retracted much more frequently than one would expect by chance. This number of flagged editors increased to 33 when mostly negative comments recorded by the watchdog PubPeer Foundation were considered.
Altogether, 45 PLOS ONE editors were flagged due to the anomalous rate at which they accepted eventually retracted or PubPeer commented publications, or because their submissions were handled by other flagged editors. Although these individuals edited only 1.3% of all papers published in PLOS ONE up to 2024, they edited a sizable 30% of the journal’s retracted papers. And 25 of these 45 editors themselves authored papers that were subsequently retracted.
These anomalous patterns are not restricted to PLOS ONE, say the Northwestern researchers. Across ten journals from the publisher Hindawi, which also disclose the editors of published manuscripts, they found 53 editors who accept eventually retracted articles anomalously often, and 96 who accept fast-tracked articles unusually frequently.
Apart from these examples of potentially fraudulent behavior, the study authors investigated whether certain scientific disciplines were more prone to fraud than others. It was found that the phenomenon is much more pronounced in six subfields in the area of RNA biology. As shown in the next figure, papers involving “lncRNAs” and “miRNAs, cancer” feature retraction rates that peak at around 4%, higher than even the rates of papers withdrawn due to errors.
Sadly, the authors conclude that scientific fraud is growing much faster than science as a whole. The number of retracted articles has been increasing exponentially over the last 30 years as seen in the figure below, in which the vertical scale is logarithmic and the dashed lines are projections.
The researchers note that the number of retracted articles and PubPeer commented articles have been doubling every 3.3 years and 3.6 years, respectively, while the total number of publications has doubled only every 15 years. The literature in some fields “may have already been irreparably damaged by fraud,” they say.
The Northwestern researchers go on to state:
Collectively, these findings show that the integrity of the extant scientific record and of future science is being undermined through the shortcomings in the very systems through which scientists infer the trustworthiness of each other’s work.
In the face of this onslaught, fortunately, the scientific community has not been silent. An informal network of research-integrity sleuths or paper-mill detectives now scrutinize thousands of published papers each year and frequently find evidence of manipulation and fabrication. Their detailed examinations, usually published online in PubPeer, often form the basis of subsequent retractions and misconduct investigations.
But sleuths and watchdog websites such as Retraction Watch can’t keep up with the rising tide of fraud. Lead author of the Northwestern study, Reese Richardson, is pessimistic about the future influence of AI (artificial intelligence):
If we're not prepared to deal with the fraud that's already occurring, then we're certainly not prepared to deal with what generative AI can do to scientific literature.
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